Peter J Connolly Selected Research

1- (4- (6- amino- 5- (methoxyiminomethyl)pyrimidin- 4- yloxy)- 2- chlorophenyl)- 3- ethylurea

1/2009

A highly selective, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor has potent activity in vitro and in vivo.

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Peter J Connolly Research Topics

Disease

10	Neoplasms (Cancer) 01/2018 - 09/2004
5	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 01/2008 - 03/2007
5	Lower Urinary Tract Symptoms 01/2008 - 03/2007
4	Prostatic Neoplasms (Prostate Cancer) 08/2021 - 10/2020
3	Pain (Aches) 01/2020 - 03/2005
3	Neoplasm Metastasis (Metastasis) 01/2009 - 09/2004
1	Colorectal Neoplasms (Colorectal Cancer) 12/2021
1	Adenoma (Adenomas) 12/2021
1	Adenocarcinoma 01/2021
1	Disease Progression 10/2020
1	Cold Hypersensitivity 01/2020
1	Hypersensitivity (Allergy) 01/2020
1	Inflammation (Inflammations) 01/2020
1	Neuralgia (Stump Neuralgia) 01/2020
1	B-Cell Lymphoma (Lymphoma, B Cell) 12/2019
1	Corneal Neovascularization 01/2009
1	Retinoblastoma (Glioblastoma, Retinal) 10/2005

Drug/Important Bio-Agent (IBA)

4	Androgen Receptors (Androgen Receptor)IBA 08/2021 - 10/2020
4	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 01/2009 - 09/2004
4	Phosphotransferases (Kinase)IBA 02/2008 - 09/2004
4	Adrenergic Antagonists (Antiadrenergic Agents)IBA 01/2008 - 06/2007
4	alpha-1 Adrenergic Receptors (alpha 1 Adrenergic Receptor)IBA 01/2008 - 03/2007
2	LigandsIBA 01/2021 - 02/2007
2	Androgen Receptor AntagonistsIBA 01/2021 - 01/2021
2	Freund's AdjuvantIBA 01/2020 - 01/2020
2	Peptides (Polypeptides)IBA 02/2007 - 03/2005
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 12/2021
1	Celecoxib (Celebrex)FDA Link 12/2021
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 12/2021
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 12/2021
1	ThiohydantoinsIBA 08/2021
1	JNJ-63576253IBA 01/2021
1	Androgen Antagonists (Antiandrogens)IBA 10/2020
1	ThiazolesIBA 01/2020
1	glyceryl 2-arachidonate (2-arachidonoylglycerol)IBA 01/2020
1	HydrolasesIBA 01/2020
1	Monoacylglycerol LipasesIBA 01/2020
1	Serine (L-Serine)FDA Link 01/2020
1	EndocannabinoidsIBA 01/2020
1	Interleukin-6 (Interleukin 6)IBA 12/2019
1	PalmitatesIBA 01/2018
1	Fatty Acid Synthases (Fatty Acid Synthase)IBA 01/2018
1	Malonyl Coenzyme A (Malonyl CoA)IBA 01/2018
1	pyrimidineIBA 04/2009
1	Tyrosine Kinase InhibitorsIBA 04/2009
1	ErbB Receptors (EGF Receptor)IBA 04/2009
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2009
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2009
1	1- (4- (6- amino- 5- (methoxyiminomethyl)pyrimidin- 4- yloxy)- 2- chlorophenyl)- 3- ethylureaIBA 01/2009
1	JNJ 28871063IBA 02/2008
1	Tyrosine (L-Tyrosine)FDA Link 02/2008
1	pyrazoleIBA 08/2007
1	benzocycloheptapyridineIBA 08/2007
1	KisspeptinsIBA 02/2007
1	JNJ-7706621IBA 10/2005
1	CDC2 Protein Kinase (Protein p34cdc2)IBA 10/2005
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 10/2005
1	Pharmaceutical PreparationsIBA 10/2005
1	Aurora KinasesIBA 10/2005
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 10/2005
1	A 17 (A-17)IBA 03/2005
1	Opioid Analgesics (Opioids)IBA 03/2005
1	Amino Acids FDA Link 03/2005
1	NociceptinIBA 03/2005
1	Doxorubicin (Adriamycin)FDA LinkGeneric 09/2004
1	4- (4- (1- Amino- 1- methylethyl)phenyl)- 2- (4- (2- morpholin- 4- yl- ethyl)phenylamino)pyrimidine- 5- carbonitrileIBA 09/2004
1	Angiogenesis InhibitorsIBA 09/2004
1	Paclitaxel (Taxol)FDA LinkGeneric 09/2004

Therapy/Procedure

4	Castration 08/2021 - 10/2020
3	Therapeutics 10/2020 - 09/2004
1	Chemoprevention 12/2021
1	Oral Administration 01/2020
1	Aftercare (After-Treatment) 09/2004